Description

2-[4-(Bromomethyl)Phenyl]Acetonitrile is a versatile and high-value organic synthetic intermediate characterized by its reactive bromomethyl and nitrile functional groups. This compound is crucial for the efficient construction of complex molecular architectures, enabling the synthesis of advanced pharmaceutical agents and specialty chemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing new active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system disorders and inflammation.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators, leveraging its phenylacetonitrile core structure.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for creating advanced organic electronic materials and liquid crystal compounds for displays.
• Cross-coupling Reactions: The bromomethyl group is highly effective in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to form biaryl structures.
• Functional Polymer Modification: Employed to introduce reactive sites onto polymer backbones for creating specialty adhesives, coatings, and resins with tailored properties.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries.

Basic Information

Product Name	2-[4-(Bromomethyl)Phenyl]Acetonitrile
CAS No.	7371-94-0
Molecular Formula	C9H8BrN
Molecular Weight	210.07 g/mol
Synonyms	4-(Bromomethyl)benzyl cyanide; p-(Bromomethyl)phenylacetonitrile; (4-Bromomethylphenyl)acetonitrile; α-Cyano-p-xylyl bromide; 2-(4-Bromomethylphenyl)acetonitrile; 4-(Bromomethyl)benzenecetonitrile; 1-Bromomethyl-4-cyanomethylbenzene; NSC 403697
EINECS	Contact for details

Quality Control

Our 2-[4-(Bromomethyl)Phenyl]Acetonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	70 - 74 °C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.