Description

Trifluoropyruvyl Fluoride is a highly reactive and versatile fluorinated building block, essential for introducing the trifluoropyruvyl moiety into complex molecular architectures. Its unique reactivity profile makes it a critical intermediate for synthesizing advanced materials and active pharmaceutical ingredients (APIs) with enhanced properties. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications requiring precise fluorination.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel fluorinated drugs, including protease inhibitors and kinase inhibitors, where the trifluoromethyl group improves metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, leveraging fluorine's ability to enhance biological activity and environmental persistence.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers, coatings, and resins with unique chemical resistance and thermal stability.
• Fluorinated Fine Chemicals: Employed in organic synthesis to create complex fluorinated molecules for research, diagnostics, and electronic chemicals.
• Ligand and Catalyst Development: Useful for synthesizing novel fluorinated ligands used in asymmetric catalysis and transition metal complexes.

Basic Information

Product Name	Trifluoropyruvyl Fluoride
CAS No.	7309-82-2
Molecular Formula	C3F4O2
Molecular Weight	144.03 g/mol
Synonyms	2,2,2-Trifluoro-1-oxoethyl fluoride; Perfluoropyruvyl fluoride; 3,3,3-Trifluoro-2-oxopropanoyl fluoride; Trifluoropyruvic acid fluoride; 2-Oxo-3,3,3-trifluoropropanoyl fluoride; TFPOF; 1,1,1-Trifluoro-2-oxo-2-fluoroethane
EINECS	Contact for details

Quality Control

Our Trifluoropyruvyl Fluoride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including GC, NMR, and FTIR, to verify identity and assay. A detailed Certificate of Analysis (COA) documenting purity, impurity profile, and physical properties is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and sources of moisture. Due to its reactivity as a fluoride/strong alkali, it should be handled and stored with appropriate precautions to prevent degradation. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Purity (GC Area %)	≥ 99.0%
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.