Description

4-Fluorophenylglycine is a high-value, non-proteinogenic amino acid derivative featuring a fluorine atom on the phenyl ring. This compound is a critical chiral building block in organic synthesis, prized for its role in introducing fluorinated aromatic motifs into complex molecules. It is essential for research and production in the pharmaceutical and agrochemical industries, where it serves as a key intermediate for active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of fluorinated drug candidates, particularly in protease inhibitors and other biologically active molecules.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides where the fluorine atom enhances stability and bioactivity.
• Peptide Mimetics & Research: Incorporated into peptide analogs to study structure-activity relationships and improve metabolic stability.
• Ligand & Catalyst Preparation: Serves as a precursor for chiral ligands used in asymmetric catalysis.
• Chemical Biology Probes: Utilized in the design of fluorinated probes for studying enzyme mechanisms and binding interactions.
• Material Science: A building block for specialty polymers and advanced organic materials requiring specific fluorinated aromatic components.

Basic Information

Item	Detail
Product Name	4-Fluorophenylglycine
CAS No.	7292-73-1
Molecular Formula	C8H8FNO2
Molecular Weight	169.15 g/mol
Synonyms	(4-Fluorophenyl)glycine; 2-Amino-2-(4-fluorophenyl)acetic acid; p-Fluorophenylglycine; 4-Fluoro-DL-phenylglycine; 4-Fluorobenzene glycine; DL-4-Fluorophenylglycine; 2-(4-Fluorophenyl)glycine; FPG
EINECS	Contact for details

Quality Control

Our 4-Fluorophenylglycine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and residual solvent screening, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.