Description

6Alpha-Hydroxyestriol is a specific hydroxylated metabolite of the endogenous estrogen, estriol. This compound is of significant interest in biochemical research and pharmaceutical development due to its role in estrogen metabolism and potential as a reference standard. It is primarily utilized by research institutions and pharmaceutical companies engaged in steroid hormone analysis, metabolic pathway studies, and the development of diagnostic assays. The product is supplied with a commitment to high purity and reliable batch-to-batch consistency.

Application

• Biochemical Research: Used as a critical reference standard in the study of estrogen metabolism and enzymatic pathways.
• Pharmaceutical R&D: Serves as an intermediate or analytical standard in the development and quality control of steroidal pharmaceuticals.
• Clinical Diagnostics: Employed in the calibration and validation of assays, such as LC-MS/MS, for the quantitative analysis of estrogen metabolites in biological samples.
• Academic Studies: Utilized in university and institutional laboratories for endocrinology and hormone-related research projects.
• Metabolite Profiling: Acts as a key component in metabolic profiling to understand estrogen-related physiological and pathological states.

Basic Information

Product Name	6Alpha-Hydroxyestriol
CAS No.	7291-49-8
Molecular Formula	C18H24O5
Molecular Weight	320.38 g/mol
Synonyms	6α-Hydroxyestriol; Estra-1,3,5(10)-triene-3,6α,16α,17β-tetrol; 6α-Hydroxy-1,3,5(10)-estratriene-3,16α,17β-triol; 6α-Hydroxy-Oestriol; 6α-OH-Estriol; 6α-Hydroxyestriol (6α,16α,17β); 6α-Hydroxy-16α,17β-estriol
EINECS	Contact for details

Quality Control

Our 6Alpha-Hydroxyestriol is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including identification by spectroscopic methods (IR, NMR) and purity assessment by HPLC, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.