Description

4-Amino-2-Methoxy-Benzonitrile is a versatile aromatic nitrile derivative that serves as a critical building block in advanced organic synthesis. Its molecular structure, featuring both an amino and a methoxy substituent, makes it a valuable intermediate for creating complex molecules with specific functionalities. This compound is essential for research and development chemists and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

The unique structure of 4-Amino-2-Methoxy-Benzonitrile provides a reactive platform for various synthetic pathways. Its primary applications include:

• Pharmaceutical Intermediate: A key precursor in the synthesis of various drug candidates, particularly those targeting central nervous system disorders and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where its benzonitrile core is a common structural motif.
• Dye and Pigment Manufacturing: Serves as a starting material for producing azo dyes and other complex colorants.
• Liquid Crystal and Electronic Material Research: Investigated as a component in the synthesis of advanced organic materials for display technologies.
• Organic Synthesis Building Block: Utilized in coupling reactions (e.g., Buchwald-Hartwig amination) and cyclization reactions to construct heterocyclic compounds.

Basic Information

Product Name	4-Amino-2-Methoxy-Benzonitrile
CAS No.	7251-09-4
Molecular Formula	C8H8N2O
Molecular Weight	148.16 g/mol
Synonyms	2-Methoxy-4-aminobenzonitrile; 4-Amino-2-methoxybenzonitrile; 4-Cyano-3-methoxyaniline; 3-Methoxy-4-cyanoaniline; 2-Methoxy-4-cyanobenzenamine; Benzonitrile, 4-amino-2-methoxy-; p-Amino-o-methoxybenzonitrile
EINECS	Contact for details

Quality Control

Our 4-Amino-2-Methoxy-Benzonitrile is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with key parameters including assay (HPLC), related substances, and physical characteristics. Our standard grade meets the requirements for use as a chemical intermediate, and we can discuss custom specifications to align with your specific project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	Light yellow to beige crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	118 - 122 °C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.