Description

Methylglucamine Metrizoate is a non-ionic, iodinated contrast agent salt primarily used in diagnostic imaging. This compound is valued for its high water solubility and relatively low osmolality, which enhances patient safety and comfort during radiographic procedures. It is a critical raw material for pharmaceutical manufacturers producing specialized contrast media for angiography, urography, and other medical imaging applications.

Application

• Pharmaceutical Intermediate: Key starting material for the synthesis of iodinated X-ray contrast media.
• Angiography Contrast Agent: Used in formulations for visualizing blood vessels and the heart.
• Urography Contrast Agent: Essential for renal imaging and diagnosing urinary tract disorders.
• Myelography: Employed in contrast media for imaging the spinal canal and subarachnoid space.
• Arthrography: Used in diagnostic procedures for joint imaging.
• Research & Development: Serves as a reference standard and building block in radiopharmaceutical research.

Basic Information

Item	Detail
Product Name	Methylglucamine Metrizoate
CAS No.	7241-11-4
Molecular Formula	C10H21I3N2O8
Molecular Weight	809.90 g/mol
Synonyms	Metrizoic Acid Meglumine Salt; Meglumine Metrizoate; Metrizoate Meglumine; N-Methylglucamine Salt of Metrizoic Acid; 1-Deoxy-1-(methylamino)-D-glucitol 3,5-diacetamido-2,4,6-triiodobenzoate; Isopaque; Triosil; Kontrast U; Contrast Medium U; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our Methylglucamine Metrizoate is manufactured under strict quality management systems. Each batch is tested to ensure it meets high-purity standards suitable for pharmaceutical applications. A comprehensive Certificate of Analysis (COA) is provided, detailing parameters such as assay, impurity profile, and residual solvents. We support compliance with ICH guidelines and relevant pharmacopoeial standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.