Description

Sodium Metrizoate is a high-purity, iodinated organic compound widely used as a key intermediate and contrast agent. Its primary value lies in its excellent water solubility and radiopaque properties, making it essential for diagnostic imaging applications. This product is critical for manufacturers in the pharmaceutical, medical device, and specialty chemical industries seeking reliable, high-quality raw materials for sensitive formulations.

Application

• X-ray Contrast Media: A vital active pharmaceutical ingredient (API) and intermediate in the synthesis of non-ionic and ionic contrast agents for angiography, urography, and computed tomography (CT) scans.
• Pharmaceutical Intermediates: Serves as a crucial building block for the synthesis of more complex iodinated diagnostic compounds.
• Research & Development: Used in biochemical and medical research laboratories for developing new diagnostic methodologies and studying radiopaque materials.
• Density Gradient Media: Can be utilized in laboratory procedures for cell separation and purification due to its ability to create precise density solutions.
• Specialty Chemical Synthesis: Employed as a reagent in organic synthesis where an iodinated aromatic structure is required.

Basic Information

Product Name	Sodium Metrizoate
CAS No.	7225-61-8
Molecular Formula	C12H10I3N2NaO4
Molecular Weight	737.93 g/mol
Synonyms	Metrizoate Sodium; Sodium 3-Acetamido-2,4,6-triiodo-5-(N-methylacetamido)benzoate; 5-Acetamido-2,4,6-triiodo-N-methylisophthalamic Acid Sodium Salt; Isopaque Sodium; Triosil; Kontrast U; Contrast U; CAS 7225-61-8
EINECS	Contact for details

Quality Control

Our Sodium Metrizoate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure it meets exacting standards for purity, identity, and consistency, suitable for pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, related substances, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); protect from humidity and absorb moisture promptly if the container is opened.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
pH (5% Solution)	6.5 - 8.5

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.