Description

3-(4-Chlorophenyl)Azetidine is a versatile nitrogen-containing heterocyclic building block of significant interest in advanced organic synthesis. Its value lies in its rigid azetidine scaffold and the reactive chlorophenyl moiety, which enable precise molecular construction for complex target molecules. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the construction of advanced herbicide and pesticide molecules, leveraging its structural features to modulate biological activity and selectivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic materials with tailored electronic or photophysical properties.
• Chemical Biology Probes: Utilized as a core structure for developing molecular probes to study enzyme function and biological pathways.

Basic Information

Product Name	3-(4-Chlorophenyl)Azetidine
CAS No.	7215-02-3
Molecular Formula	C9H10ClN
Molecular Weight	167.64 g/mol
Synonyms	3-(4-Chlorophenyl)azetidine; 1-(4-Chlorophenyl)azetidin-3-ol (tautomer); 4-Chlorophenylazetidine; Azetidine, 3-(4-chlorophenyl)-; 3-(p-Chlorophenyl)azetidine; 7215-02-3; 3-(4-Chloro-phenyl)-azetidine
EINECS	Contact for details

Quality Control

Our 3-(4-Chlorophenyl)Azetidine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.