Description

(R)-2-Benzyl-Pent-4-Enoic Acid Amide is a chiral, non-proteinogenic amino acid derivative characterized by its benzyl and pentenoic acid amide functional groups. This compound serves as a valuable chiral building block and intermediate in advanced organic synthesis, enabling the construction of complex molecules with high stereochemical fidelity. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), peptide mimetics, and other fine chemicals where precise stereochemistry is critical.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) and metabolic disorder targets.
• Peptidomimetics Research: Used to introduce constrained, non-natural amino acid residues into peptide chains to enhance stability, bioavailability, and biological activity.
• Asymmetric Synthesis: Employed as a starting material or auxiliary in catalytic asymmetric reactions to produce enantiomerically pure compounds.
• Chemical Biology Probes: Incorporated into molecular probes for studying enzyme mechanisms, receptor-ligand interactions, and other biochemical pathways.
• Agrochemical Development: Potential intermediate in the synthesis of chiral, biologically active compounds for crop protection.
• Academic & Industrial R&D: Serves as a standard or reference compound in methodological development for organic and medicinal chemistry.

Basic Information

Product Name	(R)-2-Benzyl-Pent-4-Enoic Acid Amide
CAS No.	7154-69-0
Molecular Formula	C₁₂H₁₅NO
Molecular Weight	189.25 g/mol
Synonyms	(R)-2-Benzyl-4-pentenamide; (2R)-2-Benzyl-4-pentenamide; (R)-2-Benzylpent-4-enamide; (R)-α-Benzyl-4-pentenamide; Pent-4-enoic acid, 2-benzyl-, amide, (R)-; (R)-2-Benzyl-4-pentenoic acid amide; (R)-2-Benzylpent-4-enoic acid amide
EINECS	Contact for details

Quality Control

Our (R)-2-Benzyl-Pent-4-Enoic Acid Amide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure high enantiomeric excess (ee) and chemical purity suitable for demanding synthetic applications. A detailed Certificate of Analysis (COA) providing specifications for identity, purity, and impurities is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.