Description

3-(4-Fluoro-Phenyl)-Propionic Acid Ethyl Ester is a high-purity fluorinated aromatic ester, serving as a critical building block in advanced organic synthesis. Its value lies in the unique reactivity imparted by the fluorine substituent, enabling precise molecular modifications for performance-driven applications. This compound is essential for R&D and production chemists in the pharmaceutical, agrochemical, and specialty materials sectors seeking to develop novel active ingredients and functional intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of non-steroidal anti-inflammatory drugs (NSAIDs) and other active pharmaceutical ingredients (APIs) containing fluorophenyl motifs.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides and fungicides, where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Acts as a precursor for fluorinated mesogens and electron-transport materials, crucial for high-performance display and lighting technologies.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, esterifications, and reductions to introduce the 4-fluorophenethyl moiety into complex molecular architectures.
• Flavor & Fragrance Industry: Serves as an intermediate for synthesizing specific aromatic compounds with modified scent and stability profiles.

Basic Information

Product Name	3-(4-Fluoro-Phenyl)-Propionic Acid Ethyl Ester
CAS No.	7116-38-3
Molecular Formula	C11H13FO2
Molecular Weight	196.22 g/mol
Synonyms	Ethyl 3-(4-Fluorophenyl)propionate; 4-Fluorophenylpropionic Acid Ethyl Ester; Ethyl 4-Fluorohydrocinnamate; 3-(p-Fluorophenyl)propionic Acid Ethyl Ester; Ethyl 3-(4-Fluorophenyl)propanoate; NSC 3349; Ethyl (4-Fluorophenyl)propionate
EINECS	Contact for details

Quality Control

Our 3-(4-Fluoro-Phenyl)-Propionic Acid Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chromatography and spectroscopy, to ensure high purity and consistent performance. We provide full traceability and detailed Certificates of Analysis (COA) upon request, supporting compliance in cGMP and ISO 9001 environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Density (20°C)	~1.10 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.