Description

3-Fluoro-2-Iodoanisole is a high-purity, multi-functional halogenated anisole derivative, serving as a critical building block in advanced organic synthesis. Its unique combination of fluorine and iodine substituents on the methoxybenzene ring makes it an exceptionally versatile intermediate for constructing complex molecular architectures. This compound is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and material science sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated and iodinated active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Building block for developing new-generation herbicides, fungicides, and plant growth regulators that leverage the metabolic stability imparted by the fluorine atom.
• Liquid Crystal & OLED Material Research: Serves as a starting material for creating halogenated aromatic cores used in electronic and photonic materials, including liquid crystal displays and organic light-emitting diodes.
• Cross-Coupling Reactions: The iodine moiety acts as an excellent handle for versatile palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira, Heck) to form biaryl and other conjugated systems.
• Fluorine Chemistry Exploration: Used in methodological studies to understand the directing effects and reactivity of fluorine in electrophilic aromatic substitution and metal-halogen exchange reactions.
• Radiolabeling Precursor: Potential precursor for the synthesis of compounds labeled with iodine-125 or other radioisotopes for diagnostic and research applications.

Basic Information

Product Name	3-Fluoro-2-Iodoanisole
CAS No.	7079-54-1
Molecular Formula	C7H6FIO
Molecular Weight	252.03 g/mol
Synonyms	1-Fluoro-2-Iodo-3-Methoxybenzene; 2-Iodo-3-Fluoroanisole; 3-Fluoro-2-Iodomethoxybenzene; 3-Methoxy-2-Iodofluorobenzene; Benzene, 1-fluoro-2-iodo-3-methoxy-; 1-Fluoro-3-methoxy-2-iodobenzene; 2-Fluoro-6-Iodoanisole (registry number check advised); Anisole, 3-fluoro-2-iodo-
EINECS	Contact for details

Quality Control

Our 3-Fluoro-2-Iodoanisole is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment, GC for residual solvent analysis, and 1H/19F NMR for structural confirmation, to ensure it meets the high standards required for research and scale-up applications. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, handling and packaging are performed under controlled lighting conditions to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.