Description

Methotrimeprazine Sulfoxide is a key pharmaceutical intermediate and metabolite of the phenothiazine-class antipsychotic agent, methotrimeprazine. Its significance lies in its role in drug metabolism studies, analytical reference standard preparation, and as a precursor in advanced pharmaceutical synthesis. This compound is essential for research and development laboratories, quality control units, and manufacturers in the global pharmaceutical and life sciences industries who require high-purity reference materials.

Application

• Pharmaceutical Reference Standard: Serves as a certified reference material (CRM) for the identification and quantification of methotrimeprazine and its metabolites in drug substance and product analysis.
• Metabolite Research: Critical for pharmacokinetic and pharmacodynamic studies to understand the metabolic pathway and biological activity of methotrimeprazine.
• Analytical Chemistry: Used as an analytical standard in methods development and validation for techniques like HPLC, LC-MS, and GC-MS in bioanalytical and forensic laboratories.
• Process Impurity Profiling: Employed to identify, monitor, and control sulfoxide-related impurities during the active pharmaceutical ingredient (API) manufacturing process.
• Academic & Institutional Research: Utilized in universities and research institutes for neuropharmacology studies and the development of novel analytical methodologies.

Basic Information

Product Name	Methotrimeprazine Sulfoxide
CAS No.	7052-08-6
Molecular Formula	C19H24N2OS2
Molecular Weight	360.54 g/mol
Synonyms	Levomepromazine Sulfoxide; Methotrimeprazine S-Oxide; 2-Methoxy-10-(2-methyl-3-dimethylaminopropyl)phenothiazine 5-Oxide; 5-Oxide of Levomepromazine; 7052-08-6; Levomepromazine Sulphoxide; Methotrimeprazine Sulphoxide
EINECS	Contact for details

Quality Control

Our Methotrimeprazine Sulfoxide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, assay, and impurity profile determination via chromatographic and spectroscopic methods, to ensure it meets the high standards required for research and reference material applications. A detailed Certificate of Analysis (COA) providing batch-specific results is supplied with every order.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, prolonged exposure to light and air should be avoided. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.