Description

2-Nitro-4-(trifluoromethoxy)acetanilide is a specialized aromatic nitro compound featuring a trifluoromethoxy substituent, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in its unique molecular structure, which provides a versatile scaffold for constructing more complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This high-purity intermediate is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable building blocks for complex synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the trifluoromethoxy group can contribute to improved biological activity and environmental profile.
• Chemical Research & Development: Serves as a versatile precursor for academic and industrial R&D focused on fluorinated organic compounds, heterocyclic chemistry, and material science.
• Dye and Pigment Intermediate: Can be utilized in the synthesis of specialized dyes and pigments, leveraging the nitro and acetanilide functional groups.
• Liquid Crystal and OLED Material Research: Acts as a potential starting material for developing fluorinated components used in electronic display technologies.

Basic Information

Product Name	2-Nitro-4-(trifluoromethoxy)acetanilide
CAS No.	787-57-5
Molecular Formula	C9H7F3N2O4
Molecular Weight	264.16 g/mol
Synonyms	N-(2-Nitro-4-(trifluoromethoxy)phenyl)acetamide; Acetamide, N-[2-nitro-4-(trifluoromethoxy)phenyl]-; 2-Nitro-4-trifluoromethoxyacetanilide; 4-(Trifluoromethoxy)-2-nitroacetanilide; 787-57-5; 2-Nitro-α,α,α-trifluoro-p-anisidide; N-Acetyl-2-nitro-4-trifluoromethoxyaniline
EINECS	Contact for details

Quality Control

Our 2-Nitro-4-(trifluoromethoxy)acetanilide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request, providing full traceability and assurance for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.