Description

n-Isopropyl-3-(trifluoromethyl)benzenecarboxamide is a specialized organic compound featuring a trifluoromethyl-substituted benzamide core with an isopropyl substituent on the amide nitrogen. This molecular architecture, particularly the presence of the electron-withdrawing trifluoromethyl group, makes it a valuable intermediate in advanced synthetic chemistry. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients. The compound's unique properties facilitate the development of molecules with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group can improve lipophilicity and biological activity.
• Material Science Research: Serves as a precursor for specialty polymers, liquid crystals, or organic electronic materials due to its aromatic and fluorinated components.
• Chemical Biology Probes: Utilized in the design and creation of molecular probes for studying enzyme function and protein-ligand interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	n-Isopropyl-3-(trifluoromethyl)benzenecarboxamide
CAS No.	782-70-7
Molecular Formula	C11H12F3NO
Molecular Weight	231.22 g/mol
Synonyms	3-(Trifluoromethyl)-N-isopropylbenzamide; N-Isopropyl-3-(trifluoromethyl)benzamide; m-(Trifluoromethyl)-N-isopropylbenzamide; α,α,α-Trifluoro-m-isopropylaminocarbonyltoluene; Benzamide, 3-(trifluoromethyl)-N-(1-methylethyl)-; N-(Propan-2-yl)-3-(trifluoromethyl)benzamide
EINECS	Contact for details

Quality Control

Every batch of n-Isopropyl-3-(trifluoromethyl)benzenecarboxamide is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment. Our quality commitment ensures batch-to-batch consistency and reliability for your critical development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.