Description

Pentafluorophenetole is a high-purity fluorinated aromatic ether, a key building block in advanced organic synthesis. Its unique structure, featuring a pentafluorophenyl group linked to an ethoxy moiety, makes it a versatile intermediate for creating complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors, where it is used to develop active ingredients, liquid crystals, and performance polymers.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring fluorinated aromatic systems to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides, where the introduction of fluorine atoms improves efficacy and environmental profile.
• Liquid Crystal Materials: Serves as a core building block for fluorinated liquid crystals, which are essential components in high-performance displays (LCDs) due to their improved stability and electro-optical properties.
• Polymer & Material Science: Incorporated into specialty polymers and advanced materials to impart chemical resistance, thermal stability, and unique surface characteristics.
• Organic Synthesis & Catalysis: Employed as a reagent or ligand precursor in cross-coupling reactions and catalytic processes, leveraging the electron-withdrawing nature of the pentafluorophenyl group.
• Research & Development: A valuable tool for academic and industrial R&D in medicinal chemistry and material science for exploring new chemical entities and functional materials.

Basic Information

Product Name	Pentafluorophenetole
CAS No.	776-39-6
Molecular Formula	C8H5F5O
Molecular Weight	212.12 g/mol
Synonyms	1-Ethoxy-2,3,4,5,6-pentafluorobenzene; Ethyl Pentafluorophenyl Ether; Pentafluorophenyl Ethyl Ether; 2,3,4,5,6-Pentafluorophenetole; Benzene, 1-ethoxy-2,3,4,5,6-pentafluoro-; Pentafluoroanisole, ethyl derivative
EINECS	Contact for details

Quality Control

Every batch of our Pentafluorophenetole (CAS 776-39-6) undergoes rigorous analytical testing to ensure it meets the highest standards of purity and consistency required for sensitive synthetic applications. Our quality assurance protocols are designed to guarantee reliable supply and batch-to-batch reproducibility. A comprehensive Certificate of Analysis (COA), detailing purity, identity, and impurity profiles, is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.