Description

2,3-Bis(Trifluoromethyl)Thiophene is a high-value fluorinated heterocyclic building block, distinguished by its unique electron-deficient thiophene core substituted with two trifluoromethyl groups. This compound is critical for introducing lipophilicity, chemical stability, and specific electronic properties into advanced molecular architectures. It is primarily sought after by R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the development of novel drug candidates, particularly for targets requiring enhanced metabolic stability and membrane permeability.
• Agrochemical Active Ingredient Synthesis: Used to construct advanced herbicides, fungicides, and insecticides where the trifluoromethyl groups improve biological activity and environmental persistence.
• Organic Electronic Materials: Serves as a precursor for electron-accepting units in organic semiconductors, OLEDs (Organic Light-Emitting Diodes), and OFETs (Organic Field-Effect Transistors).
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for catalysis, leveraging the electron-withdrawing nature of the substituents to tune metal center reactivity.
• Fluorinated Polymer Research: Acts as a monomer or comonomer in the research and development of high-performance, chemically resistant fluoropolymers.
• Academic and Industrial R&D: A versatile building block for exploratory chemistry in medicinal, materials, and synthetic chemistry research programs.

Basic Information

Product Name	2,3-Bis(Trifluoromethyl)Thiophene
CAS No.	773-61-5
Molecular Formula	C6H2F6S
Molecular Weight	220.14 g/mol
Synonyms	2,3-Bis(trifluoromethyl)thiophene; Thiophene, 2,3-bis(trifluoromethyl)-; 2,3-Di(trifluoromethyl)thiophene; 2,3-Bistrifluoromethylthiophene; 2,3-Bis(trifluoromethyl)-thiophene; 773-61-5; α,α,α,α',α',α'-Hexafluoro-2,3-thiophenedimethanol, cyclic bis(trifluoromethyl) ether
EINECS	Contact for details

Quality Control

Our 2,3-Bis(Trifluoromethyl)Thiophene is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing including GC, HPLC, and NMR to ensure high purity and consistency. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use and stored away from heat and ignition sources. Keep away from strong bases and reactive fluorides.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.