Description

α,α-Bis(Trifluoromethyl)-1-Aziridinemethanol is a specialized fluorinated aziridine derivative, a high-value building block in advanced organic synthesis. Its core value lies in introducing the highly stable and lipophilic bis(trifluoromethyl) group alongside a reactive aziridine ring, enabling the creation of novel compounds with tailored properties. This chemical is essential for R&D and production in pharmaceuticals and agrochemicals, where it is used to develop active ingredients with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: Key synthon for incorporating fluorine into drug candidates to improve membrane permeability and metabolic stability.
• Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science: Monomer or modifier for creating specialty polymers with unique surface properties, chemical resistance, or low dielectric constants.
• Ligand and Catalyst Development: Precursor for synthesizing novel chiral ligands and catalysts used in asymmetric synthesis.
• Fluorine Chemistry Research: A valuable reagent for academic and industrial research exploring new fluorination methodologies and novel fluorinated architectures.

Basic Information

Product Name	α,α-Bis(Trifluoromethyl)-1-Aziridinemethanol
CAS No.	773-23-9
Molecular Formula	C5H5F6NO
Molecular Weight	209.09 g/mol
Synonyms	2-(Hydroxymethyl)-1-(trifluoromethyl)-2-(trifluoromethyl)aziridine; 1-Aziridinemethanol, α,α-bis(trifluoromethyl)-; 2-(Trifluoromethyl)-2-(trifluoromethyl)aziridinemethanol; 1-(Hydroxymethyl)-2,2-bis(trifluoromethyl)aziridine; Bis(trifluoromethyl)aziridinemethanol
EINECS	Contact for details

Quality Control

Our α,α-Bis(Trifluoromethyl)-1-Aziridinemethanol is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to the reactive aziridine moiety, store separately from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.