Description

Benzene, (3,3,3-Trifluoro-1-Propynyl)- is a specialized fluorinated aromatic building block, identified by CAS NO 772-62-3. This compound is valued for its unique trifluoromethylacetylene moiety, which imparts significant electronic and steric properties, making it a critical intermediate in advanced chemical synthesis. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecules with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aromatic systems to modulate lipophilicity and bioavailability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides where the trifluoropropynyl group contributes to efficacy and environmental persistence profiles.
• Material Science Research: Serves as a monomer or precursor for developing advanced polymers, liquid crystals, and organic electronic materials with specific optoelectronic properties.
• Organic Synthesis Reagent: Employed in cross-coupling reactions, cycloadditions, and as a ligand precursor in catalysis research within fine chemical and academic laboratories.

Basic Information

Product Name	Benzene, (3,3,3-Trifluoro-1-Propynyl)-
CAS No.	772-62-3
Molecular Formula	C9H5F3
Molecular Weight	170.13 g/mol
Synonyms	(3,3,3-Trifluoro-1-propynyl)benzene; 1-(3,3,3-Trifluoroprop-1-yn-1-yl)benzene; α,α,α-Trifluoro-2-propynylbenzene; 3,3,3-Trifluoroprop-1-ynylbenzene; Phenyl(3,3,3-trifluoroprop-1-ynyl); Benzene, (3,3,3-trifluoropropynyl)-; EINECS 212-248-1
EINECS	212-248-1

Quality Control

Our Benzene, (3,3,3-Trifluoro-1-Propynyl)- is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flames. This material is moisture-sensitive; ensure containers are sealed under an inert atmosphere such as nitrogen to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.