Description

4-(tert-Butyl)Phenylacetylene is a versatile aromatic alkyne building block characterized by its tert-butyl substituted phenyl ring. This compound is highly valued in organic synthesis for its role as a key intermediate in cross-coupling reactions and material science applications. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via Sonogashira, Heck, and other palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators that incorporate acetylene and aryl motifs.
• Material Science & Organic Electronics: Serves as a monomer or building block for conjugated polymers, molecular wires, and organic light-emitting diodes (OLEDs) due to its rigid, linear alkyne functionality.
• Liquid Crystal & Polymer Chemistry: Employed in the synthesis of mesogenic compounds and specialty polymers where the tert-butyl group influences solubility and thermal properties.
• Chemical Research & Development: A fundamental reagent in academic and industrial R&D for exploring new catalytic methodologies and constructing complex organic frameworks.
• Coordination Chemistry & Ligand Design: Acts as a precursor for alkynyl ligands used in organometallic chemistry and catalysis.

Basic Information

Product Name	4-(tert-Butyl)Phenylacetylene
CAS No.	772-38-3
Molecular Formula	C12H14
Molecular Weight	158.24 g/mol
Synonyms	1-tert-Butyl-4-ethynylbenzene; p-tert-Butylphenylacetylene; 4-tert-Butylphenylacetylene; 1-(1,1-Dimethylethyl)-4-ethynylbenzene; 4-(1,1-Dimethylethyl)phenylacetylene; 4-(tert-Butyl)ethynylbenzene; 4-tert-Butylbenzeneacetylene
EINECS	212-248-1

Quality Control

Our 4-(tert-Butyl)Phenylacetylene is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing including GC, HPLC, and NMR to ensure high chemical purity and identity. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality attributes. Our commitment to consistent quality and traceability supports your R&D and scale-up processes with reliable material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.