Description

1-Ethynyl-2,4,6-Trimethylbenzene is a specialized aromatic acetylene derivative, valued for its role as a versatile building block in advanced organic synthesis. Its unique structure, featuring an ethynyl group on a sterically hindered mesitylene core, makes it a critical intermediate for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where its aromatic-acetylene framework contributes to biological activity.
• Material Science & Polymer Chemistry: Serves as a monomer or cross-linking agent in the synthesis of specialty polymers, resins, and advanced organic frameworks (MOFs/COFs).
• Ligand & Catalyst Development: Employed as a precursor for synthesizing sophisticated ligands used in homogeneous catalysis and organometallic chemistry.
• Organic Electronic Materials: A building block for π-conjugated systems used in OLEDs, organic semiconductors, and other optoelectronic devices.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D exploring new synthetic methodologies and reaction pathways.

Basic Information

Product Name	1-Ethynyl-2,4,6-Trimethylbenzene
CAS No.	769-26-6
Molecular Formula	C11H12
Molecular Weight	144.21 g/mol
Synonyms	Ethynylmesitylene; 2,4,6-Trimethylphenylacetylene; Mesitylene, ethynyl-; 1-Ethynyl-2,4,6-trimethylbenzene; 2,4,6-Trimethyl-1-ethynylbenzene; 2,4,6-Trimethylphenyl ethyne; (2,4,6-Trimethylphenyl)acetylene
EINECS	Contact for details

Quality Control

Our 1-Ethynyl-2,4,6-Trimethylbenzene is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to verify identity and purity against established specifications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place at room temperature (15-25°C). Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and potential concentration changes. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.