Description

5-Fluorobarbituric Acid is a fluorinated derivative of barbituric acid, serving as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring a fluorine atom at the 5-position, makes it a valuable building block for creating novel compounds with modified biological and physical properties. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors, particularly for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel barbiturate analogs and fluorinated active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used as a building block for developing new fluorinated pesticides and herbicides with enhanced efficacy.
• Chemical Synthesis: A versatile reagent for introducing the barbituric acid scaffold into more complex molecular architectures.
• Material Science: Potential monomer or additive in the research of specialized polymers and organic electronic materials.
• Biochemical Research: Useful in studying enzyme inhibition and as a probe in metabolic pathway studies.
• Reference Standard: Serves as a high-purity analytical standard for quality control and regulatory testing in production.

Basic Information

Product Name	5-Fluorobarbituric Acid
CAS No.	767-80-6
Molecular Formula	C4H3FN2O3
Molecular Weight	146.08 g/mol
Synonyms	5-Fluorobarbituric Acid; 5-Fluoro-2,4,6(1H,3H,5H)-pyrimidinetrione; 5-Fluoro-2,4,6-trihydroxypyrimidine; 5-Fluorobarbituric acid hydrate; 5-Fluoro-2,4,6-pyrimidinetrione; 5-Fluoromalonylurea; NSC 403697
EINECS	Contact for details

Quality Control

Our 5-Fluorobarbituric Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.