Description

4-Ethynyltoluene is a versatile aromatic alkyne building block, essential for advanced organic synthesis and materials science research. Its terminal alkyne functionality enables efficient cross-coupling reactions, making it a critical precursor for constructing complex molecular architectures. This compound is primarily utilized by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty polymer industries for applications ranging from drug discovery to the development of conductive materials.

Application

• Pharmaceutical Intermediates: Serves as a key synthon in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring arylacetylene motifs.
• Agrochemical Synthesis: Used in the production of advanced crop protection agents and herbicides, where its structure contributes to biological activity.
• Material Science & Polymers: Acts as a monomer or cross-linking agent in the development of specialty polymers, resins, and advanced materials with tailored electronic or mechanical properties.
• Organic Electronic Materials: A crucial precursor for synthesizing conjugated molecules used in organic light-emitting diodes (OLEDs), semiconductors, and photovoltaic cells.
• Chemical Research & Development: Employed in academic and industrial labs for Sonogashira, Glaser, and other metal-catalyzed coupling reactions to create novel chemical entities.
• Ligand & Catalyst Preparation: Utilized to synthesize sophisticated ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	4-Ethynyltoluene
CAS No.	766-97-2
Molecular Formula	C9H8
Molecular Weight	116.16 g/mol
Synonyms	p-Tolylacetylene; 1-Ethynyl-4-methylbenzene; 4-Methylphenylacetylene; Methyl(p-ethynylphenyl); 4-Methylbenzeneacetylene; p-Methylphenylacetylene; 4-Tolylacetylene; p-Ethynyltoluene
EINECS	212-166-3

Quality Control

Our 4-Ethynyltoluene is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to verify identity, potency, and impurity profiles. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring stringent material standards, from research to scale-up.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat, sparks, and open flame. Due to its highly volatile nature, keep container tightly sealed when not in use. Store separately from strong oxidizers and incompatible materials. Recommended storage temperature: 2-8°C (refrigerated) for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.