Description

1-Ethynyl-2-Iodo-Benzene is a versatile halogenated aromatic building block featuring both an ethynyl and an iodine functional group. This unique bifunctional structure makes it a critical intermediate for advanced organic synthesis, particularly in cross-coupling reactions and the construction of complex molecular architectures. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) via Sonogashira, Heck, and other palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and pesticides that require halogenated aromatic backbones.
• Material Science & Organic Electronics: Serves as a monomer or building block for conjugated polymers, organic light-emitting diodes (OLEDs), and other advanced organic electronic materials.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Research & Development: A valuable reagent for academic and industrial R&D in synthetic organic chemistry for constructing complex, substituted aromatic systems.
• Fine Chemical Production: Used in the multi-step synthesis of dyes, pigments, and other high-value specialty chemicals.

Basic Information

Item	Details
Product Name	1-Ethynyl-2-Iodo-Benzene
CAS No.	766-50-7
Molecular Formula	C8H5I
Molecular Weight	228.03 g/mol
Synonyms	2-Iodophenylacetylene; o-Iodophenylacetylene; (2-Iodophenyl)ethyne; 1-Ethynyl-2-iodobenzene; 2-Ethynyliodobenzene; Benzene, 1-ethynyl-2-iodo-; 2-Iodoethynylbenzene
EINECS	Contact for details

Quality Control

Our 1-Ethynyl-2-Iodo-Benzene is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality system is designed to meet the stringent requirements of GMP and ISO standards for fine chemical manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon to maximize stability.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.