Description

Trifluoromethionine is a synthetic, fluorinated analog of the essential amino acid methionine, distinguished by the substitution of three hydrogen atoms with fluorine on the methyl group. This structural modification significantly alters its biochemical properties, making it a valuable tool for advanced research and specialized applications. It is particularly sought after by researchers in pharmaceutical development, agrochemical science, and biochemistry. The compound is available under CAS NO 764-52-3 for precise identification and sourcing.

Application

• Pharmaceutical Research & Development: Used as a building block or a probe in the synthesis of novel drug candidates, especially in fluorine-based medicinal chemistry to enhance metabolic stability and bioavailability.
• Biochemical Studies: Serves as a mechanistic probe to study enzyme pathways, particularly those involving methionine metabolism and transmethylation processes, due to its altered reactivity.
• Agrochemical Innovation: Acts as a key intermediate in the development of advanced pesticides and herbicides, where the introduction of fluorine can improve activity and environmental profile.
• Proteomics & Labeling: Potential use in isotopic labeling or as a unique tag in mass spectrometry-based protein analysis and structural biology.
• Material Science Precursor: Can be utilized in the synthesis of specialized fluorinated organic compounds for advanced materials.

Basic Information

Product Name	Trifluoromethionine
CAS No.	764-52-3
Molecular Formula	C5H8F3NO2S
Molecular Weight	203.18 g/mol
Synonyms	(S)-2-Amino-4-(trifluoromethylthio)butyric Acid; L-Trifluoromethionine; 4,4,4-Trifluoro-2-amino-4-(methylthio)butyric Acid; 2-Amino-4-(trifluoromethylthio)butanoic Acid; NSC 88915; Trifluoromethionine, L-; F3-Met
EINECS	Contact for details

Quality Control

Our Trifluoromethionine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and spectroscopic identification (NMR, IR). We provide Certificates of Analysis (COA) with each shipment, detailing all specifications. Our quality systems are designed to support research and development requiring high-purity, well-characterized reference standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under anhydrous conditions when possible to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% (L-isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.