Description

Trifluoroacetylurea is a versatile fluorinated organic building block, primarily recognized for its role as a key intermediate in the synthesis of heterocyclic compounds. Its value lies in the introduction of the highly stable and electron-withdrawing trifluoroacetyl group, which can significantly alter the physical and biological properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of various nitrogen-containing heterocycles, such as pyrimidines and triazines, which are core structures in many active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances metabolic stability and bioavailability.
• Material Science: Serves as a building block for specialty polymers and advanced organic materials that require specific fluorination for improved chemical resistance or thermal stability.
• Chemical Research: Employed in academic and industrial R&D for exploring new synthetic methodologies and creating libraries of fluorinated compounds for screening.
• Dye and Pigment Industry: Acts as an intermediate in the production of specialized fluorinated dyes and pigments.

Basic Information

Product Name	Trifluoroacetylurea
CAS No.	760-41-8
Molecular Formula	C3H3F3N2O2
Molecular Weight	156.06 g/mol
Synonyms	N-(Trifluoroacetyl)urea; 1-(Trifluoroacetyl)urea; Urea, N-(trifluoroacetyl)-; Trifluoroacetic acid urea; TFAA-Urea; TFA-Urea
EINECS	212-073-8

Quality Control

Our Trifluoroacetylurea is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring full traceability and compliance with your research or production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 1.0 %
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.