Description

(±)-1,1,1-Trifluoro-2-Butanamine Hydrochloride CAS NO 758-33-8 is a high-purity chiral amine hydrochloride salt, valued as a critical fluorinated building block in advanced organic synthesis. Its unique trifluoromethyl group imparts desirable properties such as enhanced metabolic stability and lipophilicity to target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides where the fluorine moiety improves biological activity and environmental persistence.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and catalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of fluorinated polymers and specialty materials with unique surface properties.
• Chemical Biology Probes: Useful for incorporating fluorine tags into molecules for studies using techniques like 19F NMR spectroscopy.

Basic Information

Product Name	(±)-1,1,1-Trifluoro-2-Butanamine Hydrochloride
CAS No.	758-33-8
Molecular Formula	C4H7F3N·HCl
Molecular Weight	165.56 g/mol (Free base: 129.10 g/mol)
Synonyms	1,1,1-Trifluoro-2-butanamine hydrochloride; DL-1,1,1-Trifluoro-2-butanamine hydrochloride; (±)-1-Amino-1,1,1-trifluorobutane hydrochloride; 1,1,1-Trifluoro-2-aminobutane HCl; rac-1,1,1-Trifluoro-2-butanamine hydrochloride; 2-Amino-1,1,1-trifluorobutane hydrochloride; 1,1,1-Trifluoro-sec-butylamine hydrochloride
EINECS	Contact for details

Quality Control

Our (±)-1,1,1-Trifluoro-2-Butanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and scale-up applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.