Description

N,n-Dimethylthioformamide is a versatile sulfur-containing organic compound that serves as a critical reagent and building block in advanced chemical synthesis. Its unique thioamide functionality makes it valuable for introducing sulfur atoms and facilitating specific transformations that are challenging with oxygen analogs. This compound is primarily sought after by research and development laboratories and fine chemical manufacturers in the pharmaceutical and agrochemical sectors for the synthesis of complex molecules, including potential drug candidates and specialty intermediates.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of thiazole rings, heterocyclic compounds, and other sulfur-containing active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides where the thioamide group is integral to biological activity.
• Ligand and Catalyst Precursor: Acts as a precursor for ligands in coordination chemistry and catalysis, particularly in transition metal complexes.
• Organic Synthesis Reagent: Employed in various organic reactions, including as a thioacylating agent or a source of the dimethylaminothiocarbonyl group.
• Polymer Chemistry: Utilized in the research and development of specialty polymers and functional materials.
• Chemical Research: Serves as a standard or reagent in methodological development and mechanistic studies within academic and industrial R&D settings.

Basic Information

Product Name	N,n-Dimethylthioformamide
CAS No.	758-16-7
Molecular Formula	C3H7NS
Molecular Weight	89.16 g/mol
Synonyms	N,N-Dimethylthioformamide; Dimethylthioformamide; Thio-N,N-dimethylformamide; DMTF; Formamide, N,N-dimethylthio-; NSC 8648; N,N-Dimethylthioformamid; N,N-Dimethylthioformamid (German)
EINECS	212-069-8

Quality Control

Our N,n-Dimethylthioformamide is produced under stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including GC, HPLC, and NMR to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and compatible with strong acid/organic solvent environments. Keep away from heat, sparks, and open flame. For long-term storage, consider maintaining under an inert atmosphere such as nitrogen or argon to preserve purity.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%
Refractive Index (n20D)	Contact for details
Density (g/mL at 20°C)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.