Description

Trifluoperidol is a potent butyrophenone derivative belonging to the class of typical antipsychotic agents. Its primary value lies in its high-affinity antagonism of dopamine D2 receptors, making it a critical reference compound in neuropharmacological research and drug discovery. This substance is essential for researchers and developers in the pharmaceutical industry, particularly those focused on central nervous system (CNS) disorders, receptor binding studies, and the synthesis of novel therapeutic agents.

Application

• Pharmacological Reference Standard: Used as a high-purity analytical standard in quality control laboratories for the identification and quantification of trifluoperidol in pharmaceutical formulations.
• Neuroscience Research: Serves as a key tool compound in in vitro and ex vivo studies to investigate dopamine receptor function, signal transduction pathways, and the mechanisms of antipsychotic action.
• Drug Discovery & Development: Employed as a lead compound or a structural analog in the synthesis and screening of new chemical entities targeting psychiatric and neurological conditions.
• Biochemical Assays: Utilized in receptor binding assays (e.g., radioligand binding) to determine the affinity and potency of new compounds for dopamine receptors.
• Academic Research: Fundamental research in universities and institutes studying neurochemistry, psychopharmacology, and the pathophysiology of disorders like schizophrenia.

Basic Information

Product Name	Trifluoperidol
CAS No.	749-13-3
Molecular Formula	C₂₂H₂₃F₃N₂O₂
Molecular Weight	404.43 g/mol
Synonyms	Trifluperidol; Triperidol; Psicoperidol; 1-[4-(4-Fluorophenyl)-4-oxobutyl]-4-(4-hydroxy-4-(3-(trifluoromethyl)phenyl)piperidin-1-yl)piperidine-4-carbonitrile; 4'-Fluoro-4-[4-hydroxy-4-(α,α,α-trifluoro-m-tolyl)piperidino]butyrophenone; R 2498; NSC 75899
EINECS	Contact for details

Quality Control

Our Trifluoperidol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing the results against stringent in-house specifications. Our commitment ensures material integrity for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions or in a desiccator to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.