Description

Spiperone is a potent and selective dopamine D2 receptor antagonist belonging to the butyrophenone class of neuroleptic agents. This high-purity compound is critical for advanced neuroscience research and pharmaceutical development, serving as a key reference standard and pharmacological tool. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and academic sectors studying receptor binding, neuropsychiatric disorders, and drug discovery.

Application

• Pharmacological Research: Used as a selective dopamine D2 receptor antagonist in receptor binding assays and functional studies.
• Neuroscience Studies: A critical tool for investigating the role of dopamine pathways in behavior, psychosis, and movement disorders.
• Reference Standard: Serves as a certified reference material (CRM) for quality control and analytical method development in pharmaceutical labs.
• Drug Discovery & Development: Employed in high-throughput screening (HTS) and as a lead compound for developing novel antipsychotic agents.
• Biochemical Assays: Utilized in vitro to study signal transduction mechanisms and G-protein coupled receptor (GPCR) activity.
• Academic & Institutional Research: Supports fundamental research in universities and government institutions focused on neurochemistry and psychopharmacology.

Basic Information

Product Name	Spiperone
CAS No.	749-02-0
Molecular Formula	C23H26FN3O2
Molecular Weight	395.47 g/mol
Synonyms	Spiperone; Spiroperidol; Spiropitan; R 5147; 8-[4-(4-Fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one; 1'-[3-(p-Fluorobenzoyl)propyl]-1,3-dihydrospiro[2H-benzimidazole-2,4'-piperidine]; 1'-[3-(4-Fluorobenzoyl)propyl]spiro[benzimidazoline-2,4'-piperidine]-2-one
EINECS	212-041-5

Quality Control

Our Spiperone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis to ensure it meets the stringent requirements for research and development. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided to guarantee traceability, consistency, and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.