Description

Quinidine Bisulfate CAS NO 747-45-5 is a pharmaceutical-grade salt of the alkaloid quinidine, known for its antiarrhythmic properties. This high-purity compound is critical for ensuring the efficacy and safety of cardiac medications. It is primarily utilized by the pharmaceutical industry for the formulation of antiarrhythmic drugs and serves as a key reference standard in analytical and research laboratories.

Application

• Pharmaceutical Active Ingredient (API): Primary use in the formulation of oral and injectable antiarrhythmic medications for treating cardiac arrhythmias.
• Pharmacological Research: Used as a reference compound in cardiovascular research and studies on ion channel function.
• Analytical Reference Standard: Serves as a high-purity standard for quality control (QC) and assay development in pharmaceutical analysis.
• Chemical Synthesis: Acts as a chiral precursor or intermediate in the synthesis of more complex pharmaceutical molecules.
• Clinical Diagnostics: Employed in the calibration of diagnostic assays and equipment used for therapeutic drug monitoring.

Basic Information

Product Name	Quinidine Bisulfate
CAS No.	747-45-5
Molecular Formula	C20H24N2O2 • H2SO4
Molecular Weight	422.48 g/mol
Synonyms	Quinidine Hydrogen Sulfate; Quinidine Sulfate (Hemihydrate); (9S)-6'-Methoxycinchonan-9-ol Sulfate; Cinchonan-9-ol, 6'-methoxy-, (9S)-, sulfate (1:1); Quinidine Acid Sulfate; Quinidine Monosulfate; Quinidine Sulphate
EINECS	212-036-6

Quality Control

Our Quinidine Bisulfate is manufactured under strict quality management systems. It meets high-purity standards suitable for pharmaceutical applications, with rigorous testing for identity, potency, and impurities. A comprehensive Certificate of Analysis (COA) is provided with each batch, detailing results for assay, related substances, residual solvents, and other pharmacopeial parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.