Description

H-Thr-Betana CAS NO 729-25-9 is a specialized amino acid derivative, specifically a threonine-based betaine analog, valued for its role as a high-purity biochemical building block and research intermediate. Its significance lies in providing a critical chiral synthon for the synthesis of complex peptides, peptidomimetics, and other bioactive molecules where precise stereochemistry is essential. This compound is primarily needed by pharmaceutical R&D laboratories, biotechnology companies, and fine chemical manufacturers engaged in developing novel therapeutic agents, diagnostic tools, and advanced material science applications.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of novel peptide-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a building block in solid-phase and solution-phase peptide synthesis for academic and industrial research.
• Proteomics & Diagnostics: Employed in the development of specialized reagents, enzyme substrates, and molecular probes.
• Nutraceutical Development: Investigated for potential applications in formulating specialized amino acid supplements and metabolic studies.
• Material Science: Utilized in the creation of functionalized polymers and biomimetic materials requiring specific amino acid motifs.
• Asymmetric Synthesis: Acts as a chiral auxiliary or starting material in stereoselective organic synthesis.

Basic Information

Product Name	H-Thr-Betana CAS NO 729-25-9
CAS No.	729-25-9
Molecular Formula	C7H15NO4
Molecular Weight	177.20 g/mol
Synonyms	L-Threonine betaine; (2S,3R)-2-(Trimethylammonio)-3-hydroxybutanoate; O-Methyl-L-threonine betaine; L-Threoninebetaine; H-Thr(Betaine)-OH; 3-Hydroxy-N,N,N-trimethyl-L-norvaline; (2S,3R)-3-Hydroxy-N,N,N-trimethyl-2-butaniminium hydroxide inner salt
EINECS	Contact for details

Quality Control

Our H-Thr-Betana is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. The product undergoes rigorous analytical testing, including chiral purity verification, to meet the exacting standards required for pharmaceutical and research applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC), chiral purity, and residual solvent levels is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. For long-term storage, consider desiccated or inert atmosphere packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.