Description

Coenzyme Q1 is a vital benzoquinone derivative and a key member of the ubiquinone family, serving as a fundamental cofactor in mitochondrial electron transport and cellular energy (ATP) production. Its role as a potent lipid-soluble antioxidant makes it crucial for protecting cell membranes and lipoproteins from oxidative damage. This high-purity compound is essential for research and development in the pharmaceutical, nutraceutical, and life science sectors, where it is used in biochemical studies, reference standards, and as a precursor for synthesizing higher homologues like CoQ10.

Application

• Biochemical Research & Reference Standard: Used as a high-purity analytical standard in HPLC, LC-MS, and other chromatographic methods for quantifying ubiquinones in biological samples.
• Pharmaceutical Intermediate: Serves as a critical synthetic precursor in the production of higher coenzyme Q homologues, including the commercially significant Coenzyme Q10 (Ubiquinone-50).
• Cell Biology & Metabolism Studies: Employed in *in vitro* and *in vivo* research to study mitochondrial function, oxidative phosphorylation, and cellular redox signaling pathways.
• Antioxidant Mechanism Research: Investigated for its free radical scavenging properties and its role in regenerating other antioxidants like vitamin E, relevant to aging and degenerative disease models.
• Nutraceutical Formulation Development: Used in R&D for designing novel antioxidant complexes and studying the bioavailability and efficacy of coenzyme Q series compounds.
• Cosmeceutical Actives: Incorporated into advanced skincare formulations targeting oxidative stress and supporting cellular energy to promote skin vitality.

Basic Information

Product Name	Coenzyme Q1
CAS No.	727-81-1
Molecular Formula	C₁₄H₂₀O₄
Molecular Weight	252.31 g/mol
Synonyms	Ubiquinone-1; 2,3-Dimethoxy-5-methyl-6-(3-methyl-2-butenyl)-1,4-benzoquinone; CoQ1; 6-(3,3-Dimethylallyl)-2,3-dimethoxy-5-methyl-1,4-benzoquinone; 2,3-Dimethoxy-5-methyl-6-(3-methylbut-2-en-1-yl)cyclohexa-2,5-diene-1,4-dione; 1,4-Benzoquinone, 2,3-dimethoxy-5-methyl-6-(3-methyl-2-butenyl)-
EINECS	211-979-6

Quality Control

Our Coenzyme Q1 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, and is supplied with a detailed Certificate of Analysis (COA). We support compliance with relevant research and development standards, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) to minimize oxidation. Keep the container in a cool, dry, and well-ventilated area, away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Melting Point	48 - 52 °C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.