Description

n-[Bis(1-Aziridinyl)Phosphinyl]-m-Fluorobenzamide is a specialized organophosphorus compound containing both aziridine and fluorinated benzamide functional groups. This unique structure makes it a valuable intermediate for synthesizing advanced materials and biologically active molecules. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for creating novel compounds with specific activity profiles.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of experimental drug candidates, particularly those targeting enzymes or receptors where the phosphinyl-aziridine moiety can act as an alkylating agent or pharmacophore.
• Agrochemical Research: Used in developing novel pesticides and herbicides, where the fluorine atom and reactive aziridine groups can enhance biological activity and environmental stability.
• Crosslinking Agent: Serves as a reactive crosslinker in the production of specialty polymers, coatings, and resins, imparting thermal and chemical resistance.
• Bioconjugation Chemistry: Employed in biochemical research for modifying proteins, peptides, or other biomolecules due to its ability to form covalent bonds under mild conditions.
• Material Science: Intermediate for creating advanced functional materials, such as flame retardants or additives for high-performance composites.
• Chemical Synthesis Reagent: Utilized in organic synthesis laboratories as a versatile reagent for introducing phosphorus and nitrogen-containing functionalities into complex molecules.

Basic Information

Product Name	n-[Bis(1-Aziridinyl)Phosphinyl]-m-Fluorobenzamide
CAS No.	726-91-0
Molecular Formula	C11H13FN3O2P
Molecular Weight	269.21 g/mol
Synonyms	m-Fluoro-N-[bis(1-aziridinyl)phosphinyl]benzamide; 3-Fluoro-N-[bis(aziridin-1-yl)phosphoryl]benzamide; Benzamide, N-[bis(1-aziridinyl)phosphinyl]-3-fluoro-; NSC 154891; Aziridine, 1,1'-(3-fluoro-N-benzoylphosphoramidoyl)bis-; Phosphinic amide, P,P-bis(1-aziridinyl)-N-(3-fluorophenyl)-; Bis(1-aziridinyl)-3-fluorobenzoylphosphinic amide
EINECS	Contact for details

Quality Control

Our production of n-[Bis(1-Aziridinyl)Phosphinyl]-m-Fluorobenzamide adheres to stringent internal quality protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.