Description

1,1,1-Trifluoro-5-Phenyl-2,4-Pentanedione is a specialized fluorinated β-diketone compound, serving as a versatile and high-value building block in advanced organic synthesis. Its unique structure, featuring both a phenyl ring and a trifluoromethyl group, makes it a critical precursor for synthesizing complex heterocycles and fluorinated ligands. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who require precise fluorination to modify the properties of target molecules. The CAS number for this substance is 721-96-0.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated active pharmaceutical ingredients (APIs) and drug candidates, leveraging the trifluoromethyl group to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used to create advanced fluorinated pesticides and herbicides, where the fluorine atoms contribute to improved efficacy and environmental persistence.
• Ligand & Catalyst Development: Serves as a chelating agent for metal ions in the development of novel catalysts for asymmetric synthesis and polymerization processes.
• Advanced Material Precursor: Building block for fluorinated polymers, liquid crystals, and organic electronic materials, imparting desirable thermal and chemical resistance.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new fluorination methodologies and creating complex molecular architectures.

Basic Information

Product Name	1,1,1-Trifluoro-5-Phenyl-2,4-Pentanedione
CAS No.	721-96-0
Molecular Formula	C11H9F3O2
Molecular Weight	230.18 g/mol
Synonyms	5-Phenyl-1,1,1-trifluoropentane-2,4-dione; 1,1,1-Trifluoro-5-phenylpentane-2,4-dione; 5-Phenyl-1,1,1-trifluoro-2,4-pentanedione; 4,4,4-Trifluoro-1-phenyl-1,3-butanedione; Phenyltrifluoroacetylacetone; TFAA-Phenyl; F3C-CO-CH2-CO-C6H5
EINECS	Contact for details

Quality Control

Our 1,1,1-Trifluoro-5-Phenyl-2,4-Pentanedione is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system is designed to meet the stringent requirements of cGMP and ISO standards for fine chemical production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed immediately after use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	48 - 52 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.