Description

4,4,4-Trifluoro-1-(p-Tolyl)-1,3-Butanedione is a high-value fluorinated diketone building block, also known as 4,4,4-Trifluoro-1-(4-methylphenyl)-1,3-butanedione. This compound is prized for its unique chemical reactivity, serving as a versatile synthon in advanced organic synthesis. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and materials science sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated heterocycles and active pharmaceutical ingredients (APIs), leveraging the trifluoromethyl group to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the introduction of fluorine atoms is critical for efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a chelating agent for metal ions in the preparation of catalysts for asymmetric synthesis and polymerization processes.
• Advanced Material Research: Employed in the synthesis of fluorinated polymers, liquid crystals, and organic electronic materials due to its ability to modify electronic properties and solubility.
• Chemical Research & Development: A fundamental building block in academic and industrial labs for exploring new reactions and creating complex molecular architectures.

Basic Information

Product Name	4,4,4-Trifluoro-1-(p-Tolyl)-1,3-Butanedione
CAS No.	720-94-5
Molecular Formula	C11H9F3O2
Molecular Weight	230.18 g/mol
Synonyms	1-(4-Methylphenyl)-4,4,4-trifluoro-1,3-butanedione; 4,4,4-Trifluoro-1-(4-methylphenyl)-1,3-butanedione; p-Tolyltrifluoroacetylacetone; 4-Methylphenyltrifluoroacetylacetone; TTA (p-Tolyl); 1,3-Butanedione, 4,4,4-trifluoro-1-(4-methylphenyl)-; Fod (p-Tolyl derivative); β-Diketone fluorinated ligand
EINECS	211-964-4

Quality Control

Our production of 4,4,4-Trifluoro-1-(p-Tolyl)-1,3-Butanedione adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant industry standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed when not in use to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.