Description

1-(4'-Fluoro-Biphenyl-4-Yl)-Ethanone is a high-purity fluorinated aromatic ketone building block, essential for advanced organic synthesis. Its unique biphenyl core with a fluorine substituent and acetyl group makes it a versatile intermediate for creating complex molecular architectures with tailored electronic and steric properties. This compound is critical for researchers and manufacturers in the pharmaceutical and advanced materials sectors, where precise chemical functionality is paramount for developing new active ingredients and specialty polymers.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for non-steroidal anti-inflammatory drugs (NSAIDs) and other therapeutic agents.
• Liquid Crystal Materials: Serves as a core structure in the synthesis of fluorinated liquid crystals used in high-performance displays (LCDs) due to its stable biphenyl framework and fluorine atom.
• Organic Light-Emitting Diodes (OLEDs): Used as a building block for electron-transport materials and host materials in OLED devices, leveraging its conjugated system for optoelectronic applications.
• Agrochemical Synthesis: Acts as an intermediate in the production of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and environmental stability.
• Polymer Chemistry: Employed in the synthesis of specialty polymers and polyarylates, contributing thermal stability and specific solubility characteristics to the final material.
• Chemical Research: A valuable reagent in academic and industrial R&D for Suzuki-Miyaura and other cross-coupling reactions to create complex biaryl systems.

Basic Information

Product Name	1-(4'-Fluoro-Biphenyl-4-Yl)-Ethanone
CAS No.	720-74-1
Molecular Formula	C14H11FO
Molecular Weight	214.24 g/mol
Synonyms	4'-Fluoro-4-acetylbiphenyl; 4-Acetyl-4'-fluorobiphenyl; 1-(4-Fluorobiphenyl-4'-yl)ethanone; p-Fluorophenylacetophenone; 4-Fluoro-4'-acetylbiphenyl; 720-74-1; 4'-Fluorobiphenyl-4-yl methyl ketone
EINECS	Contact for details

Quality Control

Our 1-(4'-Fluoro-Biphenyl-4-Yl)-Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets the high-purity standards required for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. The container should be kept tightly sealed to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	142 - 146 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.