Description

4-(Trifluoromethoxy)Anisole (CAS NO 710-18-9) is a high-value fluorinated aromatic ether building block, prized for its unique combination of lipophilicity, metabolic stability, and electronic properties imparted by the trifluoromethoxy group. This compound is essential for advanced research and development in life sciences, enabling the synthesis of novel molecules with enhanced biological activity and physicochemical profiles. It is primarily sought after by pharmaceutical, agrochemical, and advanced material scientists for creating next-generation active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in central nervous system (CNS) and oncology therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the trifluoromethoxy group improves efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display and lighting technologies.
• Polymer & Resin Modification: Incorporated into specialty polymers to enhance chemical resistance, thermal stability, and surface properties.
• Organic Synthesis & Catalysis: A versatile reagent in cross-coupling reactions and as a ligand precursor in organometallic chemistry.
• Fluorine Chemistry Research: A standard compound for studying the effects of the -OCF3 moiety on molecular conformation and reactivity.

Basic Information

Product Name	4-(Trifluoromethoxy)Anisole
CAS No.	710-18-9
Molecular Formula	C8H7F3O2
Molecular Weight	192.14 g/mol
Synonyms	1-Methoxy-4-(trifluoromethoxy)benzene; p-(Trifluoromethoxy)anisole; 4-Methoxyphenyl trifluoromethyl ether; Anisole, 4-(trifluoromethoxy)-; Trifluoromethoxy-4-methoxybenzene; 4-Trifluoromethoxyanisole; p-Trifluoromethoxyanisole
EINECS	Contact for details

Quality Control

Our 4-(Trifluoromethoxy)Anisole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee it meets the stringent requirements for research and commercial synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.