Description

4-(Trifluoromethylsulfinyl)Chlorobenzene is a high-value organosulfur and organofluorine building block characterized by its unique trifluoromethylsulfinyl (CF3SO-) functional group. This compound matters for its critical role in advanced synthetic chemistry, enabling the introduction of both fluorine and sulfoxide motifs to modulate the physicochemical properties of target molecules. It is primarily needed by R&D and production teams in the pharmaceutical and agrochemical industries for the development of novel active ingredients, as well as by material scientists exploring specialty polymers and liquid crystals.

Application

• Pharmaceutical Intermediate: Key synthon for the synthesis of bioactive molecules, particularly in drug discovery programs targeting CNS disorders and metabolic diseases.
• Agrochemical Active Ingredient Precursor: Used in the manufacture of advanced herbicides, fungicides, and insecticides where the trifluoromethylsulfinyl group enhances lipophilicity and biological activity.
• Liquid Crystal & OLED Material Synthesis: Serves as a building block for fluorine-containing components in electronic display and lighting technologies.
• Ligand & Catalyst Development: Employed in the creation of chiral sulfoxide ligands for asymmetric catalysis.
• Polymer Modification: Incorporated into specialty polymer chains to impart specific solubility, thermal stability, or surface properties.
• Organic Synthesis Reagent: Utilized in cross-coupling reactions and as an electrophile in nucleophilic aromatic substitution for complex molecule assembly.

Basic Information

Product Name	4-(Trifluoromethylsulfinyl)Chlorobenzene
CAS No.	708-66-7
Molecular Formula	C7H4ClF3OS
Molecular Weight	228.62 g/mol
Synonyms	1-Chloro-4-(trifluoromethylsulfinyl)benzene; p-(Trifluoromethylsulfinyl)chlorobenzene; 4-Chlorophenyl trifluoromethyl sulfoxide; (4-Chlorophenyl)(trifluoromethyl)sulfoxide; Trifluoromethyl 4-chlorophenyl sulfoxide; CAS 708-66-7
EINECS	Contact for details

Quality Control

Our 4-(Trifluoromethylsulfinyl)Chlorobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.