Description

3-Chloro-4-Fluorophenylacetic Acid is a versatile fluorinated aromatic building block essential for advanced organic synthesis. This high-purity intermediate is critical for developing active pharmaceutical ingredients (APIs) and agrochemicals, where its unique halogenated structure enables precise molecular modifications. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex target molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly non-steroidal anti-inflammatory drugs (NSAIDs) and other bioactive molecules.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, leveraging the fluorine and chlorine substituents for enhanced biological activity and stability.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for display technologies.
• Organic Electronic Materials: Employed in the research and development of organic semiconductors and electro-optical materials.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D in medicinal chemistry and material science.
• Custom Synthesis: Used as a starting material for the contract manufacturing of complex, specialty organic compounds.

Basic Information

Product Name	3-Chloro-4-Fluorophenylacetic Acid
CAS No.	705-79-3
Molecular Formula	C8H6ClFO2
Molecular Weight	188.58 g/mol
Synonyms	(3-Chloro-4-fluorophenyl)acetic Acid; 2-(3-Chloro-4-fluorophenyl)acetic Acid; 3-Chloro-4-fluorobenzeneacetic Acid; NSC 403119; 705-79-3; α-(3-Chloro-4-fluorophenyl)acetic Acid
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-Fluorophenylacetic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids and organic solvents. The material is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	108 - 112 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.