Description

Tranexamic Acid is a synthetic lysine derivative that functions as a potent antifibrinolytic agent by competitively inhibiting the activation of plasminogen to plasmin. This mechanism is critical for controlling excessive bleeding and stabilizing clots in various medical and surgical contexts. It is an essential active pharmaceutical ingredient (API) for manufacturers of hemostatic drugs, topical skincare formulations, and veterinary medicines, valued for its efficacy and safety profile.

Application

• Hemostatic Agent in Medicine: Primary API in systemic and topical formulations to treat or prevent excessive bleeding in surgeries (cardiac, orthopedic, prostate), trauma, menorrhagia, and in patients with hereditary bleeding disorders like hemophilia.
• Topical Skincare Active: Incorporated into serums, creams, and lotions for its ability to inhibit melanin synthesis, effectively reducing hyperpigmentation, melasma, and post-inflammatory erythema.
• Veterinary Pharmaceuticals: Used in veterinary practice to manage bleeding episodes in companion animals and livestock during surgical procedures or due to trauma.
• Dental Applications: Employed in oral care, including mouthwashes and gels, to control bleeding following dental extractions or in patients with bleeding gums.
• Research & Development: Serves as a key reference standard and biochemical tool in pharmacological and hematological research studying fibrinolysis and coagulation pathways.
• Cosmetic Additive: Used in cosmetic products beyond medical skincare for its skin-brightening and anti-redness properties.

Basic Information

Product Name	Tranexamic Acid
CAS No.	701-54-2
Molecular Formula	C8H15NO2
Molecular Weight	157.21 g/mol
Synonyms	trans-4-(Aminomethyl)cyclohexanecarboxylic Acid; AMCHA; t-AMCHA; Tranexamic Acid; Transamin; Cyklokapron; AMCA; 4-(Aminomethyl)cyclohexanecarboxylic Acid (trans-); Ugurol; Spotgone; TXA
EINECS	211-854-3

Quality Control

Our Tranexamic Acid is manufactured under strict quality management systems. It is tested to meet high-purity standards, including relevant pharmacopeial specifications such as USP, EP, and JP. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles to ensure consistency, traceability, and regulatory compliance for pharmaceutical and cosmetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.5% - 101.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%
Optical Rotation	-0.10° to +0.10°
pH (1% Solution)	7.0 - 8.0

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.