Description

Anti-Cd4 Antibody CAS NO 74-12-4 is a highly specific monoclonal antibody designed to target the CD4 cell surface glycoprotein, a key receptor involved in T-cell activation and immune response modulation. This precision reagent is critical for research and development in immunology, enabling the study of T-cell function, autoimmune diseases, and immune checkpoint pathways. It is an essential tool for pharmaceutical developers, academic research institutions, and diagnostic manufacturers focused on advancing therapeutic and diagnostic solutions for immune-related disorders.

Application

• Immunological Research: Used for flow cytometry, cell sorting, and immunohistochemistry to identify and isolate CD4+ T-cell populations.
• Therapeutic Development: Serves as a reference standard or blocking agent in the development of novel immunotherapies and autoimmune disease treatments.
• Diagnostic Assays: Employed as a critical component in ELISA, Western blot, and other immunoassays for detecting CD4 expression levels.
• Functional Studies: Facilitates in vitro and in vivo studies of T-cell activation, signaling pathways, and immune tolerance mechanisms.
• Biomarker Discovery: Aids in research for identifying and validating CD4 as a biomarker in various disease states, including HIV and cancer.
• Quality Control: Used in the biomanufacturing sector for the characterization and release testing of cell-based therapies and other biologics.

Basic Information

Product Name	Anti-Cd4 Antibody
CAS No.	74-12-4
Molecular Formula	Contact for details
Molecular Weight	~150 kDa (approximate, IgG)
Synonyms	Anti-CD4 mAb; CD4 Monoclonal Antibody; Anti-T4 Antibody; Anti-Leu-3a; OKT4; L3T4 Antibody; T-cell Surface Glycoprotein CD4 Antibody; CD4 Receptor Antibody
EINECS	Contact for details

Quality Control

Our Anti-Cd4 Antibody is produced under stringent quality management systems. Each lot undergoes rigorous testing to ensure high specificity, purity, and biological activity, meeting the exacting standards required for research and development. Certificates of Analysis (COA) detailing purity (by SDS-PAGE and HPLC), endotoxin levels, specificity validation (e.g., by flow cytometry), and functional activity are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at 2-8°C. Avoid repeated freeze-thaw cycles. Aliquot as recommended to maintain optimal activity.

Specification

Item	Specification
Appearance	Clear to slightly opalescent liquid
Purity (SDS-PAGE)	>95%
Protein Concentration	1.0 mg/mL ± 10%
Buffer	PBS, pH 7.4
Preservative	0.09% Sodium Azide
Endotoxin Level	<1.0 EU/mg
Specificity (Flow Cytometry)	Reactivity with human CD4+ cells confirmed
Application Tested	Flow Cytometry, ELISA, Western Blot

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.