Description

Benzeneacetic Acid, α,α,2-Trifluoro-, Ethyl Ester is a high-purity fluorinated aromatic ester building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where the introduction of fluorine atoms is crucial for modulating biological activity and stability. Industrial researchers and process chemists in fine chemical and active pharmaceutical ingredient (API) manufacturing need this specialized reagent for constructing novel compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and pesticides, where the trifluoromethyl group enhances lipophilicity and biological activity.
• Liquid Crystal & OLED Material Precursor: Serves as a fluorinated aromatic core for advanced electronic materials used in displays and lighting.
• Fluorinated Polymer Modifier: Employed to introduce fluorine-containing side chains into polymers, improving their chemical resistance and surface properties.
• Organic Synthesis Reagent: A versatile reagent in cross-coupling reactions and esterification processes for constructing complex fluorinated aromatic structures.
• Chemical Research & Development: Essential for academic and industrial R&D labs exploring new fluorination methodologies and the properties of fluorinated compounds.

Basic Information

Item	Details
Product Name	Benzeneacetic Acid, α,α,2-Trifluoro-, Ethyl Ester
CAS No.	698378-76-6
Molecular Formula	C10H9F3O2
Molecular Weight	218.17 g/mol
Synonyms	Ethyl 2,2,2-Trifluoro-2-phenylacetate; α,α,2-Trifluorobenzeneacetic Acid Ethyl Ester; 2-Phenyl-2,2,2-trifluoroacetic Acid Ethyl Ester; Ethyl (2,2,2-Trifluoro-2-phenylethyl)acetate; Ethyl α,α,2-Trifluorophenylacetate; Benzeneacetic acid, α,α,2-trifluoro-, ethyl ester; Ethyl Trifluorophenylacetate
EINECS	Contact for details

Quality Control

Our Benzeneacetic Acid, α,α,2-Trifluoro-, Ethyl Ester is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including chromatography and spectroscopy, to ensure high purity and consistency suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and fluorides. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Density	~1.25 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.