Description

Ethyl 2,2-Difluoro-2-o-Tolylacetate is a high-purity fluorinated organic ester building block, essential for advanced chemical synthesis. Its value lies in the strategic incorporation of difluoromethylene and o-tolyl groups, which are critical for modulating the physicochemical and biological properties of target molecules. This compound is primarily needed by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of difluorinated analogs of biologically active molecules, potentially enhancing metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides where the difluoroacetate moiety can improve efficacy.
• Material Science Precursor: Serves as a monomer or building block for specialty polymers and advanced materials with unique surface properties.
• Organic Synthesis Reagent: Employed in cross-coupling reactions, esterifications, and as a substrate for further functional group transformations in complex molecule assembly.
• Fluorine Chemistry Research: An important compound for academic and industrial research exploring new methodologies in fluoroorganic chemistry.

Basic Information

Product Name	Ethyl 2,2-Difluoro-2-o-Tolylacetate
CAS No.	698378-71-1
Molecular Formula	C11H12F2O2
Molecular Weight	214.21 g/mol
Synonyms	Ethyl 2,2-Difluoro-2-(2-methylphenyl)acetate; 2,2-Difluoro-2-o-tolylacetic Acid Ethyl Ester; o-Tolyl(difluoro)acetic Acid Ethyl Ester; Ethyl α,α-Difluoro-o-tolylacetate; Acetic acid, 2,2-difluoro-2-(2-methylphenyl)-, ethyl ester; Ethyl 2-(2-Methylphenyl)-2,2-difluoroacetate
EINECS	Contact for details

Quality Control

Our Ethyl 2,2-Difluoro-2-o-Tolylacetate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopy (NMR, IR), to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is between 2°C and 25°C. The product is compatible with common organic solvents but should be kept in its original container to maintain integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.