Description

Benzenepropanoic Acid, 2,4-Difluoro-A is a high-purity fluorinated aromatic building block of significant interest in advanced organic synthesis. This compound is valued for its role in introducing the 2,4-difluorophenyl moiety, a key structural feature known to enhance the metabolic stability and binding affinity of target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, where the difluorophenyl group can improve lipophilicity and biological activity.
• Ligand and Catalyst Development: Serves as a building block for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of advanced polymers and liquid crystals where fluorinated aromatic units are required to modify physical properties.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.

Basic Information

Product Name	Benzenepropanoic Acid, 2,4-Difluoro-A
CAS No.	697762-59-7
Molecular Formula	C9H8F2O2
Molecular Weight	186.16 g/mol
Synonyms	2,4-Difluorohydrocinnamic Acid; 3-(2,4-Difluorophenyl)propanoic Acid; 2,4-Difluoro-β-phenylpropionic Acid; (2,4-Difluorophenyl)propanoic Acid; NSC 405124; Hydrocinnamic acid, 2,4-difluoro-; β-(2,4-Difluorophenyl)propanoic Acid
EINECS	Contact for details

Quality Control

Every batch of Benzenepropanoic Acid, 2,4-Difluoro-A is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot and provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.