Description

n-De[2-(Methylsulfonyl)Ethyl] Lapatinib is a key chemical intermediate and derivative of the tyrosine kinase inhibitor Lapatinib. This compound is of significant value in pharmaceutical research and development, particularly for the synthesis and structural modification of targeted cancer therapeutics. It is primarily needed by research institutions, pharmaceutical manufacturers, and fine chemical suppliers engaged in the development of novel oncology drugs and advanced active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis and structural optimization of Lapatinib and its novel analogs for targeted cancer therapy.
• Oncology Research: Used in biochemical and pharmacological studies to investigate structure-activity relationships (SAR) of EGFR and HER2/neu inhibitors.
• API Development: Serves as a precursor in the development and scale-up processes for new Active Pharmaceutical Ingredients (APIs) in the anti-cancer domain.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in pharmaceutical manufacturing.
• Process Chemistry: Utilized in route scouting and process optimization for the efficient commercial production of tyrosine kinase inhibitor drugs.

Basic Information

Product Name	n-De[2-(Methylsulfonyl)Ethyl] Lapatinib
CAS No.	697299-82-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Lapatinib N-De[2-(Methylsulfonyl)Ethyl] Derivative; Lapatinib Impurity; Lapatinib Related Compound; N-Desmethyl Lapatinib Sulfone Ethyl Derivative; Tykerb/Tyverb Derivative; GW572016 Derivative; EGFR/HER2 Inhibitor Intermediate
EINECS	Contact for details

Quality Control

Our n-De[2-(Methylsulfonyl)Ethyl] Lapatinib is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.