Description

3-Chloro-2-Fluorocinnamic Acid is a high-purity fluorinated cinnamic acid derivative, serving as a critical building block in advanced organic synthesis. Its unique halogenated structure makes it an indispensable intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators, leveraging its halogenated aromatic core.
• Liquid Crystal & OLED Material Research: Serves as a building block for fluorinated organic semiconductors and liquid crystal compounds due to its electron-withdrawing groups and planar structure.
• Chemical Biology & Proteomics: Employed as a versatile scaffold for designing activity-based probes and molecular tags for studying biological systems.
• Polymer Modification: Acts as a monomer or cross-linking agent for introducing fluorine and aromaticity into specialty polymers to enhance thermal stability and chemical resistance.
• Academic & Contract Research: Essential reagent for methodological development in organic chemistry, including cross-coupling reactions and fluorination studies.

Basic Information

Product Name	3-Chloro-2-Fluorocinnamic Acid
CAS No.	695187-15-6
Molecular Formula	C9H6ClFO2
Molecular Weight	200.59 g/mol
Synonyms	(2E)-3-(3-Chloro-2-fluorophenyl)prop-2-enoic acid; 3-Chloro-2-fluorocinnamic acid; trans-3-(3-Chloro-2-fluorophenyl)acrylic acid; (E)-3-(3-Chloro-2-fluorophenyl)acrylic acid; 3-Chloro-2-fluoro-trans-cinnamic acid; 2-Fluoro-3-chlorocinnamic acid; 3-Chloro-2-fluorobenzeneacrylic acid
EINECS	Contact for details

Quality Control

Our 3-Chloro-2-Fluorocinnamic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and GC/MS for residual solvent analysis, to ensure it meets the stringent requirements of research and industrial applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. For long-term storage, consider inert gas purging to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.