Description

2-[4-(2,5-Dioxo-1-Pyrrolidinyl)Phenyl]Acetonitrile is a high-purity, specialized organic building block featuring a reactive maleimide group and a nitrile functionality. This compound is critical for researchers and manufacturers requiring precise molecular assembly, particularly in the synthesis of advanced materials and bioconjugates. It is primarily utilized in pharmaceutical R&D, agrochemical synthesis, and the development of functional polymers and liquid crystals.

Application

• Pharmaceutical Intermediate: A key synthon for constructing active pharmaceutical ingredients (APIs) and antibody-drug conjugates (ADCs) via maleimide-thiol click chemistry.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and pesticides, leveraging its bifunctional reactivity.
• Polymer & Material Science: Serves as a cross-linking agent or monomer for creating specialty polymers, hydrogels, and liquid crystalline materials.
• Bioconjugation & Probe Development: Essential for labeling proteins, peptides, and other biomolecules for diagnostic assays and imaging applications.
• Organic Synthesis Building Block: Employed in academic and industrial research for constructing complex heterocycles and functionalized aromatic systems.

Basic Information

Product Name	2-[4-(2,5-Dioxo-1-Pyrrolidinyl)Phenyl]Acetonitrile
CAS No.	695150-91-5
Molecular Formula	C₁₂H₈N₂O₂
Molecular Weight	212.21 g/mol
Synonyms	4-(2-Cyanoethyl)phenylmaleimide; 1-[4-(Cyanomethyl)phenyl]-1H-pyrrole-2,5-dione; N-(4-(Cyanomethyl)phenyl)maleimide; 2-(4-Maleimidophenyl)acetonitrile; 4-Maleimidophenylacetonitrile; p-Maleimidophenylacetonitrile; CAS 695150-91-5
EINECS	Contact for details

Quality Control

Our production of 2-[4-(2,5-Dioxo-1-Pyrrolidinyl)Phenyl]Acetonitrile adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for your critical applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We are committed to meeting the rigorous demands of research and cGMP manufacturing environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases, reducing agents, and amines.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.