Description

Benzene, 2-Ethynyl-4-Fluoro-1-(Methoxymethoxy)- (9Ci) is a specialized fluorinated aromatic building block featuring both an ethynyl and a methoxymethoxy protecting group. This unique molecular architecture makes it a critical intermediate for advanced organic synthesis, particularly in the development of complex pharmaceutical and agrochemical compounds. It is primarily needed by R&D chemists and process development scientists in the life sciences sector for constructing novel molecular scaffolds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those requiring fluorinated aromatic cores.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where the fluorine atom enhances biological activity and metabolic stability.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced organic materials.
• Ligand Synthesis: Employed in the preparation of sophisticated ligands for catalysis and metal-organic frameworks (MOFs).
• Fluorine Chemistry: A valuable substrate for further functionalization via Sonogashira coupling and other cross-coupling reactions, leveraging the ethynyl group.
• Protecting Group Chemistry: The methoxymethoxy (MOM) group allows for selective protection and deprotection strategies in multi-step synthetic routes.

Basic Information

Product Name	Benzene, 2-Ethynyl-4-Fluoro-1-(Methoxymethoxy)- (9Ci)
CAS No.	694490-79-4
Molecular Formula	C10H9FO2
Molecular Weight	180.18 g/mol
Synonyms	2-Ethynyl-4-fluoro-1-(methoxymethoxy)benzene; 1-(Methoxymethoxy)-2-ethynyl-4-fluorobenzene; 4-Fluoro-2-ethynylanisole MOM ether; 2-Ethynyl-4-fluorophenyl methoxymethyl ether; 1-Fluoro-4-(methoxymethoxy)-2-ethynylbenzene; 694490-79-4; 2-Ethynyl-4-fluoro-1-(methoxymethoxy)benzene (9CI)
EINECS	Contact for details

Quality Control

Our high-purity Benzene, 2-Ethynyl-4-Fluoro-1-(Methoxymethoxy)- (9Ci) is manufactured under strict quality systems. Every batch undergoes rigorous analytical testing including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C) under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.