Description

Boronic Acid, B-(5-Methyl-1H-Indol-4-Yl)- is a high-value, heterocyclic boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its primary commercial value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to synthesize novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of drug candidates targeting various therapeutic areas, including oncology and central nervous system disorders.
• Agrochemical Synthesis: Used to create novel active ingredients for crop protection products, such as herbicides and fungicides.
• Material Science Research: Building block for the development of organic electronic materials, including OLEDs and semiconductors.
• Chemical Biology & Proteomics: Employed in the development of enzyme inhibitors, activity-based probes, and bioconjugation reagents.
• Catalyst & Ligand Development: Serves as a precursor for novel palladium catalyst ligands used in cross-coupling reactions.
• Academic & Contract Research: Fundamental reagent for methodological development and library synthesis in academic and CRO laboratories.

Basic Information

Product Name	Boronic Acid, B-(5-Methyl-1H-Indol-4-Yl)-
CAS No.	693286-67-8
Molecular Formula	C9H10BNO2
Molecular Weight	174.99 g/mol
Synonyms	(5-Methyl-1H-indol-4-yl)boronic acid; 4-Borono-5-methyl-1H-indole; B-(5-Methyl-1H-indol-4-yl)boronic acid; 5-Methyl-1H-indole-4-boronic acid; 5-Methylindole-4-boronic acid; 4-(5-Methyl-1H-indolyl)boronic acid; Boronic acid, B-(5-methyl-1H-indol-4-yl)-
EINECS	Contact for details

Quality Control

Our Boronic Acid, B-(5-Methyl-1H-Indol-4-Yl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent decomposition. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.