Description

5-Chloro-3-Cyanobenzotrifluoride is a high-value, multi-functional aromatic intermediate featuring both a cyano and a trifluoromethyl group. This unique molecular structure makes it a critical building block for synthesizing advanced materials and active pharmaceutical ingredients (APIs). It is primarily sought after by research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in areas like kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group improves biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor for fluorine-containing liquid crystal compounds used in display technologies.
• Polymer & Material Science: Incorporated into specialty polymers to impart unique chemical resistance, thermal stability, or optical properties.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to introduce the chlorobenzotrifluoride moiety into complex molecules.

Basic Information

Product Name	5-Chloro-3-Cyanobenzotrifluoride
CAS No.	693245-52-2
Molecular Formula	C8H2ClF3N
Molecular Weight	205.56 g/mol
Synonyms	3-Cyano-5-chlorobenzotrifluoride; 5-Chloro-α,α,α-trifluoro-m-toluonitrile; 2-Chloro-6-(trifluoromethyl)benzonitrile; 5-Chloro-3-(trifluoromethyl)benzonitrile; 3-Chloro-5-(trifluoromethyl)benzonitrile; 5-Chloro-α,α,α-trifluoro-3-cyanotoluene; m-Cyanobenzotrifluoride, 5-chloro- derivative
EINECS	Contact for details

Quality Control

Every batch of 5-Chloro-3-Cyanobenzotrifluoride is produced under strict quality management protocols. We employ advanced analytical techniques including GC, HPLC, NMR, and MS to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.